TRC-00664 | Protein Disulfide Isomerase (PDI) (Human) ELISA Kit | 96 Well
Product Overview
A sandwich ELISA kit for the quantitative measurement of Protein Disulfide Isomerase (PDI) in Human serum, plasma, tissue homogenates and other biological fluids.
This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. 96Trace’s PDI ELISA kit is a sandwich ELISA assay for the quantitative measurement of human PDI in serum, plasma and cell culture supernatants. The density of color is proportional to the amount of human PDI captured from the samples.
Applications
This ELISA kit is used for quantitative measurement of Protein Disulfide Isomerase (PDI) in Human serum, plasma, tissue homogenates and other biological fluids.
