TRC-00621 | Pembrolizumab (Human) ELISA Kit | 96 Well
Product Overview
A Sandwich ELISA kit for the quantitative measurement of free Pembrolizumab in human serum or plasma.
Pembrolizumab is an antibody-drug that targets the cell surface receptor programmed cell death protein 1 (PD-1) found on T cells. By preventing the binding of its ligands (PD-L1 and PD-L2), pembrolizumab induces an antitumor immune response. Upregulation of PD-1 ligands is a mechanism for tumors to evade antitumor immune response; when PD-1 binds its ligand, the T cell receives an inhibitory signal leading to T cell anergy and blockade of the anti-tumor immune response. Instead of directly targeting tumor tissue to induce tumor cell death, pembrolizumab acts as a checkpoint inhibitor to stimulate immune responses to eliminate cancer cells. Pembrolizumab ELISA kit has been developed for specific quantification of Pembrolizumab concentration in human serum or plasma with high sensitivity and reproducibility.
Assay Information
| Assay Format | Sandwich ELISA |
| Species Reactivity | Human |
| Sample Type | Human serum and plasma |
| Detection Method | Absorbance (450 nm) |
| Detection Wavelength | 450 nm |
| Kit Size | 96 Well |
Performance Data
| Detection Range | 30 - 1000 ng/ml |
| Sensitivity | 10 ng/ml |
Applications
This ELISA kit is used for quantitative measurement of Pembrolizumab in human serum and plasma
Features & Benefits
- Designed for quantitative measurement of Pembrolizumab.
- Assay format: Sandwich ELISA.
- Sample type: Human serum and plasma.
- Detection method: Absorbance (450 nm).
- Detection Range: 30 - 1000 ng/ml
- Sensitivity: 10 ng/ml
- Kit size: 96 Well.
Storage & Shipping
| Storage | +4°C |
| Shipping | Gel Pack |
| Shelf Life | 12 Months |
Product Details
| Catalog Number | TRC-00621 |
| Analyte / Target | Pembrolizumab |
| Alternate Name | PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1, PDCD1, CAS 1374853-91-4 |