PARP1 (Human) ELISA Kit

Product Overview

A sandwich ELISA kit for the quantitative measurement of PARP1 in serum, plasma, tissue homogenates and other biological fluids.

Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates the poly(ADP-ribosyl)ation of APLF and CHFR. Positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. With EEF1A1 and TXK, forms a complex that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. 96Trace’s PARP1 ELISA kit is a sandwich ELISA assay for the quantitative measurement of human PARP1 in serum, plasma and cell culture supernatants. The density of color is proportional to the amount of PARP1 captured from the samples.

Assay Information

Performance Data

Applications

This ELISA kit is used for quantitative measurement of PARP-1 in human serum, plasma, tissue homogenates and other biological fluids.

Features & Benefits

• Designed for quantitative measurement of PARP1.
• Assay format: Sandwich ELISA.
• Sample type: serum, plasma, tissue homogenates and other biological fluids.
• Detection method: Absorbance (450 nm).
• Detection Range: 0.625 – 40 ng/ml
• Sensitivity: < 0.375 ng/ml
• Kit size: 96 Well.

Storage & Shipping

Product Details