TRC-00412 | HER2 mab (Human) ELISA Kit | 96 Well
Product Overview
A sandwich ELISA kit for the quantitative measurement of HER2 mab in Human serum and plasma.
Trastuzumab (Herclon®, Herceptin®) is a recombinant DNA-derived humanized monoclonal antibody that selectively targets the extracellular domain of the human epidermal growth factor receptor 2 protein (HER2). Trastuzumab has antitumor activity against HER2-positive human breast tumor cells in laboratory models and is active for the trea™ent of women with HER2-overexpressing breast cancers. This antibody was approved in 1998 for clinical use for HER2 overexpressing metastatic breast cancer. In HER2 overexpressing cells, trastuzumab markedly down-regulates HER2 expression by accelerating receptor endocytosis and degradation and inhibits cell cycle progression by inducing the formation of p27Kip1/Cdk2 complexes. Trastuzumab ELISA kit has been developed for specific quantification of Trastuzumab concentration in human serum or plasma with high sensitivity and reproducibility.
Assay Information
| Assay Format | Sandwich ELISA |
| Species Reactivity | Human |
| Sample Type | Human serum and plasma |
| Detection Method | Absorbance (450 nm) |
| Detection Wavelength | 450 nm |
| Kit Size | 96 Well |
Performance Data
| Detection Range | 11 - 300 ng/ml |
| Sensitivity | Quantitative limit: 11 ng/ml, Detection limit: 2 ng/ml |
| Detection Limit | 2 ng/ml |
Applications
This ELISA kit is used for quantitative measurement of Trastuzumab in human serum and plasma
Features & Benefits
- Designed for quantitative measurement of HER2 mab.
- Assay format: Sandwich ELISA.
- Sample type: Human serum and plasma.
- Detection method: Absorbance (450 nm).
- Detection Range: 11 - 300 ng/ml
- Sensitivity: Quantitative limit: 11 ng/ml, Detection limit: 2 ng/ml
- Kit size: 96 Well.
Storage & Shipping
| Storage | +4°C |
| Shipping | Gel Pack |
| Shelf Life | 12 Months |
Product Details
| Catalog Number | TRC-00412 |
| Analyte / Target | HER2 mab |