Anti-Vedolizumab (Human) ELISA Kit

Product Overview

A Sandwich ELISA kit for the qualitative measurement of antibodies to Vedolizumab in human serum and plasma samples

Vedolizumab is a recombinant humanized IgG1 monoclonal antibody that targets human lymphocyte α4β7 integrin and blocks the interaction with its ligand MAdCAM-1 thus resulting in gastrointestinal anti-inflammatory activity. It is used to treat moderate-to-severe active ulcerative colitis and Crohn’s disease in patients who demonstrate an inadequate-to-no response to inhibitors of tumor necrosis factor α (TNF-α) or other conventional therapies. anti-Vedolizumab ELISA kit has been specifically developed to qualitatively determine if there are antibodies to Vedolizumab in human serum and plasma samples. The ELISA kit is based on the sandwich principle. Controls and samples are incubated in the microtiter plate coated with the drug Vedolizumab. After incubation, the wells are washed and the enzymatic activity is detected by the addition of chromogen-substrate. The enzyme-substrate reaction is terminated with an acidic stop solution. The color developed is proportional to the amount of antibodies specific for Vedolizumab present in the samples and controls. The qualitative test results can be evaluated using cut-off value.

Assay Information

Applications

This Sandwich ELISA kit is used for in vitro qualitative determination of antibodies to Vedolizumab in human serum and plasma samples

Features & Benefits

For in vitro qualitative determination of antibodies to Vedolizumab in human serum and plasma samples,Cross Reactivity: Except for Vedolizumab, there is no cross reaction with other therapeutic antibodies and native serum immunoglobins,Assay Precision: Intra-Assay and Inter-Assay CV < 30%

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