Angiotensin I (Human) ELISA Kit

Product Overview

A Sandwich ELISA kit for the quantitative measurement of Angiotensin I in human serum, plasma, culture supernatants and other biological fluids.

Angiotensinogen, also known as AGT and SERPINA8, is a member of the serpin family. It is anα-2-globulinthat is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essential component of the renin-angiotensin system (RAS) and a potent regulator of blood pressure. It is expressed by the liver and secreted in plasma. Angiotensinogen is cleaved into three chains: Angiotensin-1 (Ang I), Angiotensin-2 (Ang II), and Angiotensin-3 (Ang III). Angiotensin-1 is a substrate of ACE (angiotensin converting enzyme) that removes a dipeptide to yield the physiologically active peptide angiotensin-2. Angiotensin-1 and angiotensin-2 can be further processed to generate angiotensin-3, angiotensin-4. Angiotensin 1-7 is cleaved from angiotensin-2 by ACE2. . 96Trace’s Angiotensin-1 ELISA kit is a sandwich ELISA assay for the quantitative measurement of Angiotensin-1 in human serum, plasma and cell culture supernatants. The density of color is proportional to the amount of Angiotensin-1 captured from the samples.

Assay Information

Performance Data

Applications

This ELISA kit is used for quantitative measurement of Angiotensin I in human serum, plasma, tissue homogenates and other biological fluids.

Features & Benefits

• Easy, convenient and time-saving method to measure the level of Angiotensin I in human serum, plasma, tissue homogenates, culture supernatants and other biological fluids.
• Detection Range: 125-8000 pg/ml
• Sensitivity: < 75 pg/ml
• Assay Precision: Intra-Assay: CV < 8%; Inter-Assay: CV < 10%
• This assay has high sensitivity and excellent specificity for detection of Angiotensin I. No significant cross-reactivity or interference between Angiotensin I and analogues was observed.

Storage & Shipping

Product Details