Golimumab (Human) ELISA Kit

Product Overview

A Sandwich ELISA kit for the quantitative measurement of free Golimumab in human serum or plasma.

Golimumab is a human immunoglobulin G1κ monoclonal antibody that is specific for pro-inflammatory cytokine, tumor necrosis factor-α (TNFα). In 2009, it was approved by the FDA for the treatment of rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis in adult patients. Elevated levels of TNF are found in the synovial fluid of rheumatoid arthritis, including juvenile idiopathic arthritis, psoriatic arthritis, and ankylosing spondylitis. Pathological inflammation and joint destruction are hallmarks of these diseases. Increased levels of TNF are also found in psoriasis (Ps) plaques. Golimumab binds to both the soluble and transmembrane bioactive forms of human TNF and prevents TNF from binding to its receptors and finally inhibits the biological activity of TNF. 96Trace’s Golimumab ELISA kit has been developed for specific quantification of Golimumab concentration in human serum or plasma with high sensitivity and reproducibility.

Assay Information

Performance Data

Applications

This ELISA kit is used for quantitative measurement of Golimumab in human serum and plasma

Features & Benefits

• Designed for quantitative measurement of Golimumab.
• Assay format: Sandwich ELISA.
• Sample type: Human serum and plasma.
• Detection method: Absorbance (450 nm).
• Detection range: 100 – 3000 ng/ml
• Sensitivity: 100 ng/ml
• Kit size: 96 Well.

Storage & Shipping

Product Details