Estrogen Receptor (ERα) (Human) ELISA Kit

Product Overview

A sandwich ELISA kit for the quantitative measurement of Estrogen Receptor (ERα) in Human serum, plasma, tissue homogenates and other biological fluids.

Estrogen Receptor is a nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial association with multiprotein coactivator complexes through LXXLL motifs of their respective components. Mutual transrepression occurs between the estrogen receptor (ER) and NF-kappa-B in a cell-type specific manner. 96Trace’s ER-alpha ELISA kit is a sandwich ELISA assay for the quantitative measurement of human ER-alpha in serum, plasma and cell culture supernatants. The density of color is proportional to the amount of human ER-alpha captured from the samples.

Assay Information

Performance Data

Applications

This ELISA kit is used for quantitative measurement of ER-alpha in human serum, plasma, tissue homogenates and other biological fluids.

Features & Benefits

• Designed for quantitative measurement of Estrogen Receptor (ERα).
• Assay format: Sandwich ELISA.
• Sample type: Human serum, plasma, tissue homogenates and other biological fluids.
• Detection method: Absorbance (450 nm).
• Detection Range: 62.5-4000 pg/ml
• Sensitivity: < 37.5 pg/ml
• Kit size: 96 Well.

Storage & Shipping

Product Details