Anti-Ipilimumab (Yervoy®) (Human) ELISA Kit

Product Overview

A sandwich ELISA kit for the qualitative detection of Anti-Ipilimumab (Yervoy®) in Human serum and plasma.

Ipilimumab (Yervoy®) is a fully human IgG1κ antibody that binds to CTLA-4 (cytotoxic T lymphocyteassociated antigen 4), a molecule on T-cells that is indicated for unresectable or metastatic melanoma. The absence or presence of CTLA-4 can augment or suppress the immune system's T-cell response in fighting disease. Ipilimumab is designed to block the activity of CTLA-4, thereby sustaining an active immune response in its attack on cancer cells. The proposed mechanism of action is indirect, and may be through T-cell - mediated anti-tumor immune responses. However, some patients develop unwanted immunogenicity, which leads to production of anti-drug-antibodies (ADAs) inactivating the therapeutic effects of the treatment and, in rare cases, inducing adverse effects. 96Trace’s BioSimTM anti-Ipilimumab ELISA kit is designed to detect antibody against Ipilimumab with high specificity and sensitivity in biological matrices.

Assay Information

Applications

This ELISA kit is used for qualitative detection of Anti-Ipilimumab (Yervoy®) in Human serum and plasma.

Features & Benefits

• Designed for qualitative detection of Anti-Ipilimumab (Yervoy®).
• Assay format: Sandwich ELISA.
• Sample type: Human serum and plasma.
• Detection method: Absorbance (450 nm).
• Kit size: 96 Well.

Storage & Shipping

Product Details