Anti-Golimumab (Simponi®) (Human) ELISA Kit

Product Overview

A sandwich ELISA kit for the qualitative detection of Anti-Golimumab (Simponi®) in Human serum and plasma.

Golimumab (Simponi®) is a human immunoglobulin G1κ monoclonal antibody which is specific for pro-inflammatory cytokine, tumor necrosis factor-α (TNFα). Elevated levels of TNF are found in the synovial fluid of rheumatoid arthritis, including juvenile idiopathic arthritis, psoriatic arthritis, and ankylosing spondylitis patients and play an important role in both the pathologic inflammation and the joint destruction that are hallmarks of these diseases. Golimumab binds to both the soluble and transmembrane bioactive forms of human TNF and prevent TNF from binding to its receptors and finally inhibits biological activity of TNF. However, some patients develop unwanted immunogenicity, which leads to production of anti-drug-antibodies (ADAs) inactivating the therapeutic effects of the treatment and, in rare cases, inducing adverse effects. 96Trace’s BioSimTM anti-Golimumab ELISA kit is designed to detect the antibody against Golimumab with high specificity and sensitivity in biological matrices.

Assay Information

Applications

This ELISA kit is used for qualitative detection of Anti-Golimumab (Simponi®) in Human serum and plasma.

Features & Benefits

• Designed for qualitative detection of Anti-Golimumab (Simponi®).
• Assay format: Sandwich ELISA.
• Sample type: Human serum and plasma.
• Detection method: Absorbance (450 nm).
• Kit size: 96 Well.

Storage & Shipping

Product Details