Anti-Denosumab (Prolia®) (Human) ELISA Kit

Product Overview

A sandwich ELISA kit for the qualitative detection of Anti-Denosumab (Prolia®) in Human serum and plasma.

Denosumab (Prolia®) is a human monoclonal antibody that binds to RANKL, a transmembrane or soluble protein essential for the formation, function, and survival of osteoclasts, the cells responsible for bone resorption. Prolia prevents RANKL from activating its receptor, RANK, on the surface of osteoclasts and their precursors. Prevention of the RANKL/RANK interaction inhibits osteoclast formation, function, and survival, thereby decreasing bone resorption and increasing bone mass and strength in both cortical and trabecular bone. However, some patients develop unwanted immunogenicity, which leads to production of anti-drug-antibodies (ADAs) inactivating the therapeutic effects of the treatment and, in rare cases, inducing adverse effects. 96Trace’s BioSimTM anti-Denosumab ELISA kit is designed to detect antibody against Denosumab with high specificity and sensitivity in biological matrices.

Assay Information

Applications

This ELISA kit is used for qualitative detection of Anti-Denosumab (Prolia®) in Human serum and plasma.

Features & Benefits

• Designed for qualitative detection of Anti-Denosumab (Prolia®).
• Assay format: Sandwich ELISA.
• Sample type: Human serum and plasma.
• Detection method: Absorbance (450 nm).
• Kit size: 96 Well.

Storage & Shipping

Product Details