TRC-00007 | 17-Hydroxyprogesterone ELISA Kit | 96 Well
Product Overview
A competitive ELISA kit for the quantitative measurement of 17-Hydroxyprogesterone in extracted serum and plasma, or in urine, extracted dried fecal samples, and tissue
The adrenal glands, ovaries, testes, and placenta produce 17-hydroxyprogesterone. It is hydroxylated at the 11 and 21 position to produce cortisol. Deficiency of either 11- or 21-hydroxylase results in decreased cortisol synthesis, and feedback inhibition of adrenocorticotropic hormone (ACTH) secretion is lost. Consequent increased pituitary release of ACTH will increase production of 17-HOP. But, if 17-alpha-hydroxylase (which allows formation of 17-HOP from progesterone) or 3ß-hydroxysteroid dehydrogenase type 2 (which allows formation of 17-hydroxyprogesterone formation from 17-hydroxypregnenolone) are deficient, 17-HOP levels are low with possible increase in progesterone or pregnenolone respectively. 96Trace’s 17-Hydroxyprogesterone ELISA kit is a competitive ELISA assay for the quantitative measurement of 17-Hydroxyprogesterone in extracted serum and plasma, or in urine, extracted dried fecal samples, and tissue culture media samples.
Applications
This ELISA kit is used for quantitative measurement of human total 17-HOP in extracted serum and plasma, or in urine, extracted dried fecal samples, and tissue
